2 edition of Studies on the interferon-alpha/beta system of pigs found in the catalog.
Studies on the interferon-alpha/beta system of pigs
Series of papers combined to form a thesis for the Biomedical Center, Swedish University of Agricultural Sciences, Uppsala.
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Surface studies of novel hydrophobic active carbons Applied Surface Science, vol , Issue 7, pp. () Vaccination with recombinant adenoviruses expressing Ebola virus glycoprotein elicits protection in the interferon alpha/beta receptor knock-out mouse Book Chapter High performance carbon nanotube - polymer nanofiber. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families. type I interferon production interferon-alpha production The appearance of interferon-alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
The present invention relates to rapid clearance molecules that bind target antigens and FcγRIIb with increased affinity as compared to parent molecules, the compositions being capable of causing accelerated clearance of such antigens. Such compositions are useful for treating a variety of disorders, including allergic diseases, atherosclerosis, and a variety of other conditions. JPB2 JPA JPA JPB2 JP B2 JP B2 JP B2 JP A JP A JP A JP A JP A JP A JP B2 JP B2 JP B2 Authority JP Japan Prior art keywords fc antibody antibodies fc variants binding Prior art date Legal status (The legal status is an Cited by:
Nicotiana tabacum is a stout annual of the TOMENTOSAE family, approx 1–3 m high. The stem is erect with few branches. Leaves are ovate, elliptic, or lanceolate, up to cm or more in length, usually sessile or sometimes petiolate with frilled wing or auricle. Persistent porcine reproductive and respiratory syndrome virus (PRRSV) infection in pigs does not require significant genetic change. J Swine Health Prod 17(6) Chen Z, Zhou X, Lunney JK, Lawson S, Sun Z, Brown E, Christopher-Hennings J, Knudsen D, Nelson EA.
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The Effects of Interferon-α2a on Concentrations of Immunoglobulins, Complement and Lymphocytes in Patients with Multiple Sclerosis February Scandinavian Journal of Immunology 59(1) Studies from other groups have shown that co-treatment of IFN improves the anti-tumor effects of chemotherapeutic agents such as doxorubicin and etoposide .Author: Hans Strander.
Porcine reproductive and respiratory syndrome virus (PRRSV) is not only a poor inducer of type I interferon but also inhibits the efficient induction of type I interferon by porcine transmissible gastroenteritis virus (TGEV) and synthetic dsRNA molecules, Poly I:C.
However, the mechanistic basis by which PRRSV interferes with the induction of type I interferon in its natural host cells remains Cited by: 9. Type I interferons (IFNs) were identified more than 50 years ago by Isaacs and Lindenmann as a soluble factor that can interfere with viral replication and is able to block infection.
Meanwhile, type I IFNs are broadly recognized for their antiviral. To interpret undesired alterations of the immune system, comprehension of the histophysiology of the system is required. Table gives an overview on histophysiology and compartments of the thymus, spleen, lymph nodes, mucosa-associated lymphoid tissue (MALT), tertiary lymphoid tissues, and lymphoid cells in omental adipose tissue.
In addition, the immune histophysiology of nonlymphoid. The hallmark of arenaviruses is their tendency to cause persistent silent infections in their natural hosts (rodents) and severe, often lethal, disseminated disease in humans.
Arenaviruses are pleomorphic enveloped particles that contain two RNA segments of virus origin and ribosome-like components. Suitable conditions for transmission of virus to humans occur in areas where humans come in.
Murine respirovirus, formerly Sendai virus (SeV) and previously also known as murine parainfluenza virus type 1 or hemagglutinating virus of Japan (HVJ), is an enveloped, nm in diameter, a negative sense, single-stranded RNA virus of the family Paramyxoviridae.
It typically infects rodents and it is not pathogenic for humans or domestic : Monjiviricetes. Studies of steroid excretion in AN have indicated reduced activity of the oxidation component of 11β-HSD interferon alpha/beta, platelet factor 4, Also in pigs, breed-specific basal plasma cortisol concentrations exist (Sutherland et al., ).
Arboviruses are arthropod-borne viruses that exhibit worldwide distribution and are a constant threat, not only for public health but also for wildlife, domestic animals, and even plants. To study disease pathogenesis and to develop efficient and safe therapies, the use of an appropriate animal model is a critical concern.
Adult mice with gene knockouts of the interferon α/β (IFN Cited by: 1. The Cardiovirus genus is divided into two species: the Encephalomyocarditis species, which includes encephalomyocarditis virus (EMCV) and mengovirus, and the Theilovirus species, which includes Theiler’s murine encephalomyelitis virus (TMEV), Vilyuisk human encephalomyelitis virus (VHEV), and Saffold virus (SAFV).
This chapter discusses members of the Cardiovirus genus and distinctive Cited by: 7. Interferons play an important role in the first line of defense against viral infections. They are part of the non-specific immune system (as are lysozyme, complement, etc.) and are induced at an early stage in viral infection — before the specific immune system has had time to respond.
Interferons themselves are not antiviral antibodies. This chapter discusses how influenza virus infection triggers the production of type I interferon (IFNs), the signaling cascades that the cytokines stimulate to establish a protective antiviral response, and the mechanisms that orthomyxoviruses employ to circumvent the host's innate immunity.
Orthomyxoviruses employ several strategies to circumvent the host’s innate and adaptive immune Cited by: 3. Japanese encephalitis virus (JEV) is a zoonotic virus that cycles in nature among birds, pigs, and other vertebrate hosts via mosquito vectors, but it also infects humans, who develop fetal encephalitis.
Pigs are a primary natural host for JEV, with transplacental infection of the fetus during pregnancy affecting fetal development. Today, JEV is one of the most important emerging zoonotic.
The authors of the study found that, compared to the controls, mice given Interferon alpha,beta 10X produced a statistically significant increase in all of the specific immune response variables measured.
Day C. Stillbirth in Pigs. and fixed tissues of victims of the flu. Characterization of five of the eight RNA segments of the influenza virus indicates that it was the common ancestor of both subsequent human and swine H1N1 lineages, and experiments testing models of virulence using reverse genetics approaches with influenza genes have begun in hopes of identifying genetic features that confer virulence.
Book chapters Davies-Tuck M, Davey M, Fernandez JA, Reddy M, Caulfield M and Wallace E () Ethnicity, obesity, and pregnancy outcomes on fetal programming. In Diet, Nutrition, and Fetal Programming. Eds: Rajendram R, Preedy VR and Patel VB.
Humana Press, USA, pp Funder JW () Aldosterone and mineralocorticoid receptors. In Stress: Neuroendocrinology and. Enter search terms. Keep search filters New search. Advanced search.Current topics in microbiology and immunology, ISBNVolumeix, OTHER PUBLICATIONS: Pastorino et al.
(Cancer Research ;IDS). * McLaughlin et al. (Blood ; ). * Fabio et al., “Doxorubicin-loaded fab' fragments of anti-disialoganglioside immunoliposomes selectively inhibit the growth and dissemination of human neuroblastoma in nude mice,” Database Biosis, Biosciences Information Service, Philadelphia, PA.
The present invention relates, in general, to attenuated swine influenza viruses having an impaired ability to antagonize the cellular interferon (IFN) response, and the use of such attenuated viruses in vaccine and pharmaceutical formulations. In particular, the invention relates to attenuated swine influenza viruses having modifications to a swine NS1 gene that diminish or eliminate the.
NASA Images Solar System Collection Ames Research Center. Brooklyn Museum. Full text of "Mount Sinai Journal of Medicine" See other formats.NASA Images Solar System Collection Ames Research Center. Brooklyn Museum. Full text of "Aerospace medicine and biology: A cumulative index to a continuing bibliography (supplement )".The present invention relates to Fc region-containing polypeptides that exhibit improved effector function due to alterations in the degree of fucosylation, and methods of using such polypeptides to treat or prevent cancer and other diseases.
The Fc region-containing polypeptide of the invention is preferably an immunoglobulin (such as an antibody), wherein the Fc region comprises at least one Author: 레슬리 에스. 존슨, 가드프리 조나 앤더슨 레이니, 라우라 러너, 세르게이 고르라토브.